In 2019, there were an estimated 229 million cases of malaria and 409,000 malaria-related deaths in 87 countries.
Following a sustained trend toward the reduction of malaria from 2005 to 2014, the region of the Americas has experienced an increase in the total number of cases and deaths since 2015. This is mainly an effect of the massive increase in transmission and outbreaks in areas with complex socio-political and economic challenges and, recently, compounded by other challenges brought about by the COVID-19 pandemic. Much like the global trend, progress on the achievement of target reductions in malaria burden has stalled since 2015. In 2019, the region reported a total of 816,000 cases and 197 deaths, compared to 453,000 cases and 159 deaths in 2015.